Experimental Design Details for GSE317499 - Degradation of perineuronal nets in hippocampal CA2 explains the loss of social cognition memory in Alzheimer's disease

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Dataset Name Degradation of perineuronal nets in hippocampal CA2 explains the loss of social cognition memory in Alzheimer's disease
Description
Loss of social cognition memory impairs Alzheimer's disease (AD) patients to recognize family members, friends, and caregivers. We investigate the role of perineuronal nets (PNNs), specialized coats of extracellular matrix around hippocampal CA2 neurons in AD‐associated social memory impairments. At time of import, last updated (by provider) on: Jan 28 2026 Contributors: ; [Jiang Shan, Cope Elise, Sontheimer Harlad, Kasprzak Izabela, Escalante Miguel, Prim Courtney, Li Jiangtao, Fleischel Erik, Hou Silky, Chaunsali Lata, Tewari Bhanu, Olsen Michelle]
Accession GSE317499 GEO logo
Publication Chaunsali, Lata et al. (2025) PubMed Link