N-(6-butyl-1H-benzimidazol-2-yl)carbamic acid methyl ester delivered at dose 0.054 uM of GSE96760 - H-STS NET cell line perturbed with small molecule compounds

N-(6-butyl-1H-benzimidazol-2-yl)carbamic acid methyl ester delivered at dose 0.054 uM (subset of GSE96760 - H-STS NET cell line perturbed with small molecule compounds, see all subsets)

Annotations:

SUBSET, bulk RNA-seq assay, parbendazole

Description:

Expression profile of H-STS NET cell line at 6h and 24h after perturbation with small molecule compounds.
At time of import, last updated (by provider) on: May 15 2019

Contributors: ; [Mariano J Alvarez] (inherited)
                        

Accession:

GSE96760

(inherited)

Publication:

Alvarez, Mariano J et al. (2018)

(inherited)

Dimension:

42387 (4/573 samples)

Other subsets:

(2,3-dichlorophenyl)-[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1-indolyl]methanone delivered at dose 5.4 uM
1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea delivered at dose 0.25 uM
1-[6-(2-hydroxypropan-2-yl)-2-pyridinyl]-6-[4-(4-methyl-1-piperazinyl)anilino]-2-prop-2-enyl-3-pyrazolo[3,4-d]pyrimidinone delivered at dose 0.08 uM
1h-indole-5-sulfonamide, n-(3-chlorophenyl)-3-[[3,5-dimethyl-4-[(4-methyl-1-piperazinyl)carbonyl]-1h-pyrrol-2-yl]methylene]-2,3-dihydro-n-methyl-2-oxo-, (3z)- delivered at dose 1.52 uM
2-[(2S)-1-[3-ethyl-7-[(1-oxido-3-pyridin-1-iumyl)methylamino]-5-pyrazolo[1,5-a]pyrimidinyl]-2-piperidinyl]ethanol delivered at dose 0.009 uM
2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-9-pyrido[1,2-a]pyrimidinyl]ethyl]amino]benzoic acid delivered at dose 0.322 uM
3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-3-piperidinyl]-2-thiophenecarboxamide delivered at dose 0.03 uM
4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one delivered at dose 0.065 uM
4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one delivered at dose 0.65 uM
4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxybenzoic acid delivered at dose 0.044 uM
4-[hydroxy-[4-[[4-[[(1-naphthalenylamino)-oxomethoxy]methyl]phenyl]methylamino]butyl]amino]-4-oxo-2-butenoic acid methyl ester delivered at dose 0.072 uM
4-[hydroxy-[4-[[4-[[(1-naphthalenylamino)-oxomethoxy]methyl]phenyl]methylamino]butyl]amino]-4-oxo-2-butenoic acid methyl ester delivered at dose 0.72 uM
5-[6-[(4-methyl-1-piperazinyl)methyl]-1-benzimidazolyl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]-2-thiophenecarboxamide delivered at dose 0.01 uM
5-[6-[(4-methyl-1-piperazinyl)methyl]-1-benzimidazolyl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]-2-thiophenecarboxamide delivered at dose 0.05 uM
5Z-7-oxozeaenol delivered at dose 0.22 uM
6-[[4-[(3-methylsulfonylphenyl)methylamino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-3,4-dihydro-1H-quinolin-2-one delivered at dose 2.08 uM
7-(3,5-dimethyl-4-isoxazolyl)-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-3H-imidazo[4,5-c]quinolin-2-one delivered at dose 0.88 uM
7-(3,5-dimethyl-4-isoxazolyl)-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-3H-imidazo[4,5-c]quinolin-2-one delivered at dose 1.32 uM
AZD-8055 delivered at dose 2 uM
AZD-8055 delivered at dose 20 uM
BGJ-398 delivered at dose 4.56 uM
BI2536 delivered at dose 0.009 uM
BIO delivered at dose 3 uM
BKM120 delivered at dose 1.2 uM
BMS-754807 delivered at dose 0.72 uM
Bafetinib delivered at dose 3.24 uM
Bardoxolone methyl delivered at dose 0.15 uM
CD437 delivered at dose 0.236 uM
CHM-1 delivered at dose 0.084 uM
DBeQ delivered at dose 1.6 uM
FK866 delivered at dose 20 uM
Gossypol delivered at dose 4.44 uM
INC280 delivered at dose 20 uM
JNJ-26854165 delivered at dose 0.6 uM
KHS101 delivered at dose 1.2 uM
KX2-391 delivered at dose 0.024 uM
Ku-0063794 delivered at dose 0.04 uM
LSM-1131 delivered at dose 0.0709 uM
LSM-1131 delivered at dose 0.709 uM
MK-2206 delivered at dose 0.684 uM
MK-2206 delivered at dose 6.84 uM
ML-210 delivered at dose 0.04 uM
N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1-tetrazolecarboxamide delivered at dose 0.64 uM
N-(2-phenylphenyl)-8-[4-(3-pyridinyl)-1-triazolyl]octanamide delivered at dose 7.4 uM
N-(4-methoxyphenyl)sulfonyl-N-[2-[2-(1-oxido-4-pyridin-1-iumyl)ethenyl]phenyl]acetamide delivered at dose 0.1 uM
N-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[(2-methyl-4-thieno[3,2-d]pyrimidinyl)amino]-1,4-dihydropyrrolo[3,4-c]pyrazole-5-carboxamide delivered at dose 0.008 uM
N-[3-[[(2,3-dihydroxyphenyl)-oxomethyl]amino]phenyl]-2,3-dihydroxybenzamide delivered at dose 1.68 uM
N-[4-(2-tert-butylphenyl)sulfonylphenyl]-2,3,4-trihydroxy-5-[(2-propan-2-ylphenyl)methyl]benzamide delivered at dose 4 uM
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal delivered at dose 0.25 uM
N1'-[3-fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide delivered at dose 0.214 uM
N3-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine delivered at dose 0.06 uM
NVP-231 delivered at dose 0.028 uM
NVP-231 delivered at dose 0.27 uM
Nutlin-3 delivered at dose 0.84 uM
Obatoclax delivered at dose 0.068 uM
Obatoclax delivered at dose 0.68 uM
PAC-1 delivered at dose 4 uM
PHA-665752 delivered at dose 2.88 uM
Piplartine delivered at dose 1.04 uM
Ribociclib delivered at dose 26.32 uM
SB-743921 delivered at dose 0.0004 uM
SCH-529074 delivered at dose 0.48 uM
SNX-2112 delivered at dose 0.006 uM
SNX-2112 delivered at dose 0.066 uM
Y-27632 delivered at dose 3.36 uM
YM-155 delivered at dose 0.00006 uM
YM-155 delivered at dose 0.0007 uM
[4-[2-(1H-indazol-3-yl)ethenyl]phenyl]-(1-piperazinyl)methanone delivered at dose 5.52 uM
afatinib delivered at dose 1 uM
alpelisib delivered at dose 19.4 uM
alvocidib delivered at dose 0.048 uM
arachidonyl group delivered at dose 7.44 uM
belinostat delivered at dose 0.00325 uM
belinostat delivered at dose 0.0325 uM
bexarotene delivered at dose 20 uM
bortezomib delivered at dose 0.0088 uM
bortezomib delivered at dose 0.02 uM
brefeldin A delivered at dose 0.042 uM
brivanib delivered at dose 7 uM
ceritinib delivered at dose 2.8 uM
cerulenin delivered at dose 0.68 uM
ciclopirox delivered at dose 5 uM
crizotinib delivered at dose 0.48 uM
dasatinib (anhydrous) delivered at dose 0.004 uM
docetaxel trihydrate delivered at dose 0.002 uM
doxorubicin delivered at dose 0.008 uM
entinostat delivered at dose 0.684 uM
entinostat delivered at dose 6.84 uM
epigallocatechin gallate delivered at dose 15.12 uM
erastin delivered at dose 10 uM
erastin delivered at dose 15 uM
everolimus delivered at dose 5.88 uM
fingolimod delivered at dose 4 uM
fluvastatin delivered at dose 0.76 uM
gemcitabine delivered at dose 0.05 uM
gemcitabine delivered at dose 0.15 uM
ibrutinib delivered at dose 2.4 uM
imatinib delivered at dose 2 uM
imatinib delivered at dose 20 uM
istradefylline delivered at dose 20 uM
leptomycin B delivered at dose 0.00012 uM
linifanib delivered at dose 5 uM
luminespib delivered at dose 0.02 uM
manumycin A delivered at dose 4.32 uM
midostaurin delivered at dose 2.84 uM
mithramycin delivered at dose 0.024 uM
mitomycin C delivered at dose 0.44 uM
necrosulfonamide delivered at dose 4 uM
neratinib delivered at dose 0.25 uM
nilotinib delivered at dose 7.68 uM
onalespib delivered at dose 0.07 uM
paclitaxel delivered at dose 0.003 uM
panobinostat delivered at dose 0.005 uM
parthenolide delivered at dose 0.8 uM
pictrelisib delivered at dose 0.05 uM
pluripotin delivered at dose 0.005 uM
reference substance role
rigosertib delivered at dose 0.1 uM
rosiglitazone delivered at dose 20 uM
sorafenib delivered at dose 3.72
sunitinib delivered at dose 0.176 uM
sunitinib delivered at dose 1.76 uM
topotecan delivered at dose 0.00138 uM
topotecan delivered at dose 0.0138 uM
vincristine delivered at dose 0.0008 uM
vorinostat delivered at dose 0.2 uM

Assays:

Annotations:

Category	Value
study design	SUBSET (inherited)
assay	bulk RNA-seq assay (inherited)