Class ExpressionExperimentPlatformSwitchService


  • @Service
    public class ExpressionExperimentPlatformSwitchService
    extends ExpressionExperimentVectorManipulatingService
    Switch an expression experiment from one array design to another. This is valuable when the EE uses more than on AD, and a merged AD exists. The following steps are needed:
    • Delete old analyses of this experiment and processeddata vectors
    • For each array design, for each probe, identify the matching probe on the merged AD. Have to deal with situation
    • where more than one occurrence of each sequence is found.
    • all DEDVs must be switched to use the new AD's design elements
    • all bioassays must be switched to the new AD.
    • update the EE description
    • commit changes.
    • Computed processed data vectors
    This also handles the case of multisamples-per-platform - NOT the case of one-sample-per-platform but multiple platforms; for that you have to run VectorMerging. For more nutty situations this will probably create a mess.
    Author:
    pavlidis
    See Also:
    VectorMergingService
    • Field Detail

      • NULL_BIOSEQUENCE

        public static final BioSequence NULL_BIOSEQUENCE
        Used to identify design elements that have no sequence associated with them.
    • Constructor Detail

      • ExpressionExperimentPlatformSwitchService

        public ExpressionExperimentPlatformSwitchService()
    • Method Detail

      • switchExperimentToArrayDesign

        @Transactional
        public void switchExperimentToArrayDesign​(ExpressionExperiment ee,
                                                  ArrayDesign arrayDesign)
        If you know the array designs are already in a merged state, you should use switchExperimentToMergedPlatform
        Parameters:
        ee - ee
        arrayDesign - The array design to switch to. If some samples already use that array design, nothing will be changed for them.
      • switchExperimentToMergedPlatform

        @Transactional
        public ArrayDesign switchExperimentToMergedPlatform​(ExpressionExperiment expExp)
        Automatically identify an appropriate merged platform
        Parameters:
        expExp - the experiment to switch to a merged platform
        Returns:
        the selected merged platform the experiment was switched to