QuantileNormalizer (Gemma 1.31.4 API)

java.lang.Object
- ubic.gemma.core.analysis.preprocess.normalize.QuantileNormalizer<R,C>

```
public class QuantileNormalizer<R,C>
extends Object
```
Perform quantile normalization on a matrix, as described in:
Bolstad, B (2001) _Probe Level Quantile Normalization of High Density Oligonucleotide Array Data_. Unpublished manuscript PDF
Bolstad, B. M., Irizarry R. A., Astrand, M, and Speed, T. P. (2003) _A Comparison of Normalization Methods for High Density Oligonucleotide Array Data Based on Bias and Variance._ Bioinformatics 19(2) ,pp 185-193. web page. However, note that this deals with missing values differently than the Bioconductor implementation.

Author:

pavlidis

See Also:

MatrixNormalizer

- Constructor Summary
  
  Constructors
  Constructor Description
  
  QuantileNormalizer()
- Method Summary
  
  All Methods Instance Methods Concrete Methods
  Modifier and Type Method Description
  
  DoubleMatrix<R,C> normalize(DoubleMatrix<R,C> dataMatrix)
  - Methods inherited from class java.lang.Object
    clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait

Constructor Detail
- QuantileNormalizer
```
public QuantileNormalizer()
```

Method Detail

normalize

public DoubleMatrix<R,C> normalize(DoubleMatrix<R,C> dataMatrix)